Formulation of long-wavelength indocyanine green nanocarriers

Indocyanine Green (ICG)-Loaded Nanocarriers as Optical Contrast Agents for Enhancing Breast Cancer Detection

Breast cancer is the most common malignancy in women worldwide and one of the main leading causes of cancer deaths in the USA. Optical imaging in the near infrared spectrum provides tumor functional information at the tissue and molecular level needed for early breast cancer detection. Early detection will significantly reduce the breast cancer mortality. To enhance the detection sensitivity an...

Indocyanine Green: Observations

Indocyanine green 1 (ICG) is a tricarbocyanine dye (Figure 1) which has been used in the indicator dilution technique for measuring cardiac output (1, 2). Animal studies (3) and preliminary observations of human subjects (4, 5) have suggested that this dye may have characteristics that could make its uptake, storage, and excretion by the liver helpful indices of hepatic function. The present in...

Indocyanine green accused.

T he concept of retinal vital staining is not new. There has however been renewed interest in the subject since indocyanine green (ICG) was introduced as a vital stain to highlight the internal limiting membrane (ILM) during macular surgery. ICG’s well known role in cardiac and choroidal angiography exploits its properties as a fluorophore, but its role as a macular vital stain relies on its pr...

Indocyanine green angiography.

A brief survey of the recent ophthalmic literature underscores a resurgence of interest in indocyanine green angiography (ICGA). This imaging method may be particularly useful for the ophthalmologist, as it provides at least a theoretical advantage for improved imaging of the choroidal circulation when compared with fluorescein angiography. New temporal and spatial technological advances (that ...

Retina: indocyanine green (ICG) angiography.